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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK2
All Species:
28.18
Human Site:
S494
Identified Species:
77.5
UniProt:
P78362
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78362
NP_872633.1
688
77543
S494
H
D
R
S
R
T
V
S
A
S
S
T
G
D
L
Chimpanzee
Pan troglodytes
XP_001160812
687
77411
S493
H
D
R
S
R
T
V
S
A
S
S
T
G
D
L
Rhesus Macaque
Macaca mulatta
XP_001088614
687
77455
S493
H
D
R
S
R
T
V
S
A
S
S
T
G
D
L
Dog
Lupus familis
XP_849273
686
77402
S492
H
D
R
S
R
T
V
S
A
S
S
T
G
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O54781
681
76738
S487
H
D
R
S
R
T
V
S
A
S
S
T
G
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508534
693
78060
S499
H
D
R
S
R
T
V
S
A
S
S
T
V
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165329
695
78154
S500
Q
D
R
S
R
T
V
S
A
S
S
T
G
D
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
T669
E
D
V
T
M
E
D
T
V
N
E
N
G
N
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
N532
N
T
M
D
S
N
S
N
V
S
T
D
I
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.6
N.A.
93.9
N.A.
N.A.
87.8
N.A.
80.7
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
99.4
99.2
96.5
N.A.
95.4
N.A.
N.A.
91.9
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
89
0
12
0
0
12
0
0
0
0
12
0
78
0
% D
% Glu:
12
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% G
% His:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% L
% Met:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
12
0
12
0
12
0
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
78
0
78
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
0
0
78
12
0
12
78
0
89
78
0
0
0
12
% S
% Thr:
0
12
0
12
0
78
0
12
0
0
12
78
0
0
0
% T
% Val:
0
0
12
0
0
0
78
0
23
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _